Pathology of the Lungs
Congenital Anomalies
Vascular Diseases
Atelectasis
Obstructive Lung Disease
Restrictive Lung Disease
Neoplasia
Etiology
Small Cell Carcinoma
Non-small cell Lung Carcinoma
Clinical Course
silent and insidious
initial symptoms
chronic cough & sputum
late symptoms
hoarseness
chest pain
superior vena caval syndrome
compression/ infiltration of superior vena cava
pericardial/ pleural effusion
inflammation & exudation from invasion
segmental atelectasis
Pancost Syndrome
brachial/cervical plexus involvement
pain in distribution of ulnar nerve
Horner Syndrome
sympathetic trunk involvement
1st & 2nd rib destruction
Paraneoplastic Syndrome
PTH-related peptide
hypercalcemia
Cushing's
SIADH
Cerebellar degeneration
peripheral sensory & motor neuropathy
proximal myopathy & dermatomyositis
Finger Clubbing
Poor prognosis