DEFINITION: the bacteria adaption for DNA transfer thats depends on the expression of numerous bacterial genes which results will carry out this process.
Haemophilus Influenza : the first gram negative bacterium in which natural competence was found. It's facultatively anaerobic bacterium that can cause severe infection.
MECHANISM (Neisseria Gonorrhea)
2
STEP 1: Transfer DNA from surface to the cytoplasmic membrance.
STEP 2: DNA translocation across cytoplasmic membrance is highly conserved. -ComA in Neisseria Gonorrhoeae is mediated by homologuse. ComE act as DNA binding proteins feeding ComA channel. -PriA may pull ssDNA into cytoplasm on the expense of ATP, incoming ssDNA is protected by binding proteins.
STEP 3: The pillus assembled by a complex which comprises at least the ATPase PiLF ,the integral membrance protein PiLG and a peptidase for pilin processing.
STEP 4: Species-specific adaptation for transfer DNA to cytoplasmic membrance.
