In 1803 a Philidelphiean man, John Conrad Otto was the first person to publish an article on the hemmorhagic bleeding disorded that primarly affected men. He managed to track it back to a woman from New Hamshire in 1720.
In 1901 the US surgeon catalogue listed lime, inhaled oxygen, and the use of either thyroid gland or bone marrow, hydrogen peroxide or gelatin as a treatment.
In 1937 Arther Patek and FHL Taylor published an article describing anti- hemophellia globin that was found in plasma.
By the late 1950s- 1960s hemophellia patients in hostpitals were transfused with fresh frozen plasma.
In 1965 Dr. Judith Graham Pool published a paper on a major breakthrough, she discovered that precipitate left from thawing plasma was rich in factor VII, which is a clotting factor naturally produced by the liver.
For those affected by hemophilla there are plenty of support groups that are there to help those with hemophilla to be able to live a normal life.
The Canadian Hemopkilla society (CHS) is a charity with the main goal of helping to improve the lives of those who've been affected by hemophilia.
At the moment there are only temporary remedies, no permantant cure. For people with hemophellia they have options that will help such as blood thickeners but there is no cure. Right now there is research being done to try to find a cure. There are many ways that someone could help, primarly by donating to research for a cure.
Right now there is research being done to use gene therapy to genetically engeneer metamyucal cells ( the adult stem cells) so that they produce a factor of VIII. This will be an amazing blood clotter and possible become a full on cure for patients.
Hemophilia A
Hemophilia a is caused by a disruption in the f8 gene. This gene is responsible for creating a protein called factor VII which is responsible for aiding blood clotting as response to injury.
Hemophilia B
Hemophilia b is the second most common version of hemophilia. This is version of hemophilia is cause by a disruption of the f9 gene which produces factor IX, another protein responsible for aiding in blood clotting.
Hemophilia C
Hemophilia c is the rarest of the three hemophilia variants. It is the result of a disruption in the f11 gene, causing a reduced production of factor XI. Factor XI is another protein aiding in the clotting of blood.
What's The
Difference?
All different types of hemophilia affect different genes, hemophilia a the f8 gene, hemophilia b the f9 gene, and hemophilia c the f11 gene. The other major difference is that while hemophilia a and b are an x-linked pattern, hemophilia c affects chromosome 4. This results in both females and males having the same effects as apposed to hemophilia a and b.
the causes for this is because, the blood doesn't clot the same way as it would normally. this is because it doesn't have enough blood clotting proteins. you also might bleed longer than someone if you have hemophilia
Causes: hormone imbalance, disfunction of ovaries, pregnancy complications, cancer, inherited bleeding disorders, medications and other medical conditions.
some causes of this causes of this: kidney infections, enlarged prostate, urine tract (bladder) infection, some medicines, a blood disease, like sickle cell anemia.
causes: trauma or injury, like a sprain, fracture, or torn ligament, surgery, including arthroscopic surgery, a bleeding disorder, such as hemophilia, medications used to prevent blood clots (blood thinners) such as warfarin, certain infections.