TREATMENT OF DM: ORAL HYPOglycaemics

Honelako gehiago

diabetic

nadia yadollahi‑k egina

Listening

Екатерина Нарывская‑k egina

The 1920's & 1930's

Claire Gallagher‑k egina

Describing animals

Silvia Defano‑k egina

TREATMENT OF DM: ORAL HYPOglycaemics

Alpha GluCOSidase Inhibitors

BIGuANIDES

Prandial Glucose Regulators (PGR)

SulphoNYLureas

S.Es

Secondary failure rate = 5-10% per yr

Hypoglycaemia

WEIGHT GAIN by increasing inulin secretion

Shud not give glibenclamide & chlorpropamide (=long-acting) 2 over 70s if live alone - fatal

Effective, well-tolerated & widely used

No lag period b4 response

High initial response

INCREASE insulin secretion

Examples:

ChlorPROpaMIDE

TolBUTAmide

GliPIzide

GliCLAzide

GliBENclaMIDE

ThiaZOlidiNEdiones (GlitaZONES)