EFFECT OF FREE RADICALS

Honelako gehiago

DNA Generalities

Montoya Tobón Montoya Tobón‑k egina

New Map

Erik Buys‑k egina

Organigram

Hugo Oyarzabal‑k egina

Biochemical Reactions

Anastasiya Dyadchenko‑k egina

EFFECT OF FREE RADICALS

PTN cross linking

cystine - lysine - methionine - histidine

enzyme inactivation :Sulfa-hydral enzyme

DNA damage

3- Mutations or cell Killing

2- single strand DNA

1- free radical with thymine =Oxidation

Non-peroxidative mito mem damage

Fenton reaction

Xanthene oxidase

lipid peroxidation of Membranes

free radical attach to double bond of mem form : Lipid peroxide

this LIPID peroxide: unstable & Reactive= extensive damage to All membranes