作者:Retaj mohammed 2 年以前
318
EFFECT OF FREE RADICALS
EFFECT OF FREE RADICALS
PTN cross linking
cystine - lysine - methionine - histidine
enzyme inactivation :Sulfa-hydral enzyme
DNA damage
3- Mutations or cell Killing
2- single strand DNA
1- free radical with thymine =Oxidation
Non-peroxidative mito mem damage
Fenton reaction
Xanthene oxidase
lipid peroxidation of Membranes
free radical attach to double bond of mem form : Lipid peroxide
this LIPID peroxide: unstable & Reactive=
extensive damage to All membranes