Kategoriak: Guztiak - synthesis - purification - reduction

arabera Tony Zoltika 18 years ago

425

Rearrangements

None

Rearrangements

Reduction of ketone

Johnson

- cyclization of carboxylic acid to cyclic ketone

Saucy-Marbet

- rearrangement

- synthesis of Grignard-reagent

- treatment with Grignard-reagent of aldehyde

- cyclization of product to alkyl-laktone

- reduction of aldehyde with NaBH4

- cyclization of second OH to lactone

Ireland

- acylation and purification
- LDA synthesis and actual rearrangement

- purification

- cyclization of (alkyl) carboxylic acid to alkylated cyclic ketone

ester hydrolysis