Stimulants

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Pharmacology of Antipsychotics

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Stimulants

Amphetamines

ecstacy

"suicide tuesday"

swamps the 5HT receptors that are involved in sexual arousal

increase serotonin (blocks the transporterprotein that removes it

alertec

not recomended for normal fatigue

take one before bed then feel refreshed after 4-5 hours of sleep

"smart pills"

methamphetamine

increase dopamine and distroys it's transports

10-15mg doses

ice, speed...

benzedrine

decrease fatigue

increase respiration, heart rate, Bp, alertness, and cocentration

for narcolepsy

5,10,15mg oral doses

PPA

17x increase risk of stroke

was common in cold remidies

phenylproponolamine

Ephedrine

increase risk of heartfibs and sroke

adrenergic agonists

Adrenalin

increase BP, clears nose, increse alertness

epinephrine

Cocaine

synergistic with alcohol

increases heartrate, body temp., dialates pupils

Prevents the re-uptake of dopamine and adrenalyn

Note: Snow cooked with NaHCO3 makes crack

Cocaine.HCL

25-100mg dosages

lasts abotu one hour

mp 195degrees

snorted, injected, rubbed into gums

Free Base

lasts about 10 minutes

fast acting

smoked

Nicotine

releases dopamine, increase indorphins

acettlycholine agonist

>heart reate, BP, breathing rate,

rapid relese of adrenalin

biphasic (excites and calms)

Caffene

LD50=200mg/kg

inhibits PDE(Heart enzyme that breaks down c-AMP.

200mg

Strychinine

powerful

extremily bitter

smile of death

Viagra

blocks PDE-5(penis) ha ha

Zyban

releases dopamine

inhibits re-uptake of adrenalyn

stop smoking agent

150mg/day