Diabetes Insipidus UNMC Group 9

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Case Study

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Diabetes Insipidus

Neurogenic

Severe Symptoms

Desmopressin, hormone that replaces ADH

Mild Symptoms

Increase Water Intake

Brain Injury

Genetic errors in brain

When synthesis and release of ADH are reduced

Symptoms

Constipation

Frequent Urination

Dilute Urine

Nocturia

Excessive Thirst

Confirmatory Testing

MRI

ADH Blood level

Water Deprivation Test

Nephrogenic

Treatment

Microzyde

Low Salt Diet

Causes

Medications, especially ones containing lithium

Cancer

Kidney Infection

Kidney Cysts

Genetic errors in kidney function

Normal synthesis of ADH but a defective renal tubular response to ADH.

Lab Findings

Urine chemistry will be low for electrolytes

Lower glucose when compared to Diabetes Mellitus

Low specific gravity