Wound Healing

Plus de détails

ASTHMA 2

par Fabiola Aguilar Jimenez

Smoking

par Theodore Chien

Immunology

par Ravi Chacko

Reconstruction

par Madeline Adams

Phase III: Remodeling and Maturation

Occurs several weeks after injury.

Assembly and remodeling of the cellular matrix

Process can be delayed by certain medications including steroids and NSAIDS

Systemic Response

Natural Barriers

First Line of Defense

Inflammatory Process: Phase I

Reconstruction: Phase II

Proliferation and new tissue growth 3-4 days post Injury

Granulation tissue growth MMPs breakdown extracellular matrix proteins

Angiogenesis factors

stimulate vascular endothelial buds growing into wound

Fibroblasts stimulated by transforming growth factor-beta

Wound Healing

Second line of defense

Rapid Response

Subtopic

Conclusion of inflamation

Result of Tissue Injury

Epithelial barrier damaged