ACE inhibitor

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Winter 2015 Pathophys Concept Map

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ACE Inhibitor Renal Scintigraphy

Optional manuevers

2 day study may be employed

If ACE Inhibited Study is abnormal, basline may be performed next day

If it is normal, then no baseline is necessary

Patient Prep

Pt should be well hydrated

NPO 4 hrs

ACE Inhibitors should be held

Enaliprat/Lisinopril

1 week

48 hrs

Imaging Protocol

Post-void

Upright

500k counts

Dynamic

10-30 sec/frame->30minutes

Flow

1-3 sec/frame->30frames

Contraindications

Patient Motion

Pregnant/Breastfeeding

Indications

Renal Hypertension

Critical Organ

Bladder wall

Instrumentation

128x128 matrix

Dynamic/Flow

LEHR

LFOV

Imaging Techniques

Kidneys near top of FOV

Patient Supine

Image Posterior

Analysis

Abnormal Study:

Lingering Uptake after administration of ACE inhibitor RPH not washing out

Normal Study:

RPH should wash out regardless of ACE inhibitor

Captopril

imaging begins 1 hour after

25-50mg taken orally

Radiopharmaceuticals

99mTc-MAG3

1-10 mCi

(1mCi if doing 1day baseline study)

99mTC-DTPA

1-10mCi