a Jasmine Juliette 4 éve
327
Class Assignment JAMJ Endo Sp 21
Mrs. D, 48yo with severe constipation with Calcium level of 11.2
Treatment complications
Chronic Hypocalcemia needing lifelong
supplementation of Ca2+ and Vitamin D
Recurrent Laryngeal nerve injury
Hypoparathyroidism
Additional Labs and Results
EKG - shortened QTi, Tall T waves, bradyarrythmias
DEXA - osteoporosis
XR - decreased bone density or normal
PTHrP - increased in malignancy
PTH - increased PTH
Urine: Hypercalciuria, Hyperphosphauria
Serum: Hypercalcemia, Hypophosphatemia, Low 20(OH) Vitamin D
Other Questions to ask the patient
Are you having headaches or feeling
like you've had memory changes?
Are you feeling tired or depressed lately?
Any heart palpitations?
Any bone pain, muscle weakness or muscle pain?
Treatment
Surgical Exploration +/- Partial Parathyroidectomy
pt meets criteria for surgery
Endocrinology consult!
PE Findings
Shortened QT intervals
Fatigue
Abdominal pain, nausea and/or vomiting
Muscle weakness and atrophy
Decreased DTR's
Mild bone pain
DDx
Malabsorption Disease
MEN syndrome
Malignancy - Parathyroid adenoma, metastasis
Vitamin D intoxication
Primary Hyperparathyroidism