Drugs in body

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Animal systems

Szerző: Virina Maged Atia Malty

Vertebrates: Phylogenetic Tree

Szerző: Kayla DS

HPT Axis Team 12

Szerző: Aiman Khan

Pharmacokinetics (cont.)

Szerző: McKay Blatter

Drugs in body

Liver

formation of metabolites for excretion

- primary organ for drug metabolism

Cells

- intracellular drug activity and impact

- cellular uptake of drugs

Fat

- fat-soluble drugs have specific distribution patterns

- lipophilic drugs may accumulate in fatty issues

Enzymes

- drug metabolism affects bioavailability

- enzymatic processes in the liver metabolize drugs

Small Intestine

- interaction with intestinal enzymes

- absorption of drugs into the bloodstream

Protein

- influences on drug availability

- blinding of drugs to plasma proteins

Receptors

- initiation of pharmacological effects

- interaction of drugs with specific receptors

Stomach and Stomach Acid

- impact of stomach acidity on drug stability

- initial drug exposure in the stomach

Circulatory System

- rapid distribution throughout the body

- bloodstream transport of drugs