a KHYRE JACKSON 1 éve
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Drugs in body
Drugs in body
Liver
formation of metabolites for excretion
- primary organ for drug metabolism
Cells
- intracellular drug activity and impact
- cellular uptake of drugs
Fat
- fat-soluble drugs have specific distribution patterns
- lipophilic drugs may accumulate in fatty issues
Enzymes
- drug metabolism affects bioavailability
- enzymatic processes in the liver metabolize drugs
Small Intestine
- interaction with intestinal enzymes
- absorption of drugs into the bloodstream
Protein
- influences on drug availability
- blinding of drugs to plasma proteins
Receptors
- initiation of pharmacological effects
- interaction of drugs with specific receptors
Stomach and Stomach Acid
- impact of stomach acidity on drug stability
- initial drug exposure in the stomach
Circulatory System
- rapid distribution throughout the body
- bloodstream transport of drugs