Pharmacodynamics

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principles of Pharmacology

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Pharmacodynamics

therapeutic index

TI = LD50 / ED50

effective dose

lethal dose

half - life elimination

50% of drug

drug - drug interaction

chemical incompatibility

synergism

adverse effects

good or bad

no safe drug

allergic reaction

toxicity

drug - response relationships

serum concentration - time profile

therapeutic range

toxic level

peak serum concentration

minimum effective concentration

duration of action

termination of action

onset of action or latent period

potency

efficacy

mechanisms of action

nonspecific drug interactions

drug - enzyme interactions

stimulation or blockage occurs

drug - receptor interactions

antagonist

agonist

affinity