viruses

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Viruses and Cancer

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viruses

Types of viral infection

viruses and cancer

metastasis

anaplasia

neoplasia

tumor

infection in eukaryotic cells

transformation to malignant cell

infection in bacteria and Archeae

Archeae Viruses

lysogenic conversion

virion structure

virion genome

circular

Segmented

RNA

DNA

virion enzymes

viral envelopes

viral envelope protein

Subtopic

animal virus envelope

flexible, membranous layer

capsid

complex symmetry

icosahedral

helical

structure

Envelopes

contain nucleocapsid (DNA and RNA)

Prions

Neural loss

Proteinaceous Infectious Particle

viroids and satellites

encode one or more gene products

infectious nucleic acids (DNA / RNA)

requires host cell

do not encode gene

infectious agents of closed, circular ssRNAs

Cultivation and Enumeration of viruses

hosts for

plant viruses

plant protoplast cultures

plant tissue cultures

animal viruses

embryonated eggs

cytopathic effects

tissue cultures

bacterial and Archaea

agar cultures

requires inoculation of appropriate living host

Viral multiplication

virion release

assembly

synthesis stages

viral entry and uncoating

Attachment (Adsorption)

mechanism

Accelular Agents

prions

satellites

viroids

eukaryotic viruses

bacteriophages

virion

nucleocapsid (DNA and RNA)

size: 10-400nm