The text discusses various types of antimicrobial chemotherapy methods, which include antibacterial, antihelmintic, antiviral, antifungal, and antiprotozoal agents. Each type of antimicrobial has specific characteristics and mechanisms of action.
Target organism
Mode of Action
Origin
Example of Antibiotic
Cidal and static activity
Spectrum of Action
ANTIMICROBIAL CHEMOTHERAPY METHODS
Classification of Antibiotics
General properties of an ideal antibiotic
no allerginicity - the molecule should not cause an alllergic reaction. minimal irritation.
sold at a reasonable cost -it should be cost effective and readily available.
should hve a long shelf life- shoulf not be light,temperature sensitive
bacteria should not develop resistance to the drug
should not harm or eliminate normal flora
Should be efffective in the presences of body fluids and exudates
chemotherapeutic index-the efficacy of the molecule should always overcome the toxic reactions or adverse reactions
the antibiotic should exhibit selective and effective antimicrobial activity
Definition
involve the administration of drugs with selective toxicity agaianst pathogens involved in infectiion , not host cells .