Drug Administration-psg

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Drug Administration

Biopharmaceutics

Gas

Ex: Oxygen, Anesthesia, Aerosol Inhalers

Liquid

Suspension

Emulsion

Solution

Solid

Suppositories (Inserts)

Vaginal

Rectal

Troches

Pastille

Lozenge

Capsules

Soft Gelatin

Hard Gelatin

Tablets

Buccal (Sublingual)

Effervescent

Controlled release

Multiple Compressed

Enteric coated

Film coated

Sugar coated

Compressed

Pharmacokinetics

Disintegration and Dissolution

Metabolism (Biotransformation)

Intestinal Mucosa

Lungs

Kidneys

Liver

Conjugation

Oxidation, Hydrolysis, or Reduction

Distribution

BARRIERS

Placental Barrier

Blood-Brain Barrier

Factors

Drug Reservoirs

Bone Tissue

Fat Tissue

Plasma

Regional Blood Flow

Cardiac Output

Absorption

Compatibilty

Lipophilicity

Acid-Base Properties

Concentration

Blood Flow

Surface Area