Categories: All - bacteria

by zulaikha hashim 14 years ago

983

STAPHYLOCOCCUS

STAPHYLOCOCCUS

STAPHYLOCOCCUS AUREUS

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Cultural Characters

  • facultative anaerobe
  • usually grows in simple nutrient media

    • selective indicator mannitol

  • can tolerate high conc. of NaCl
  • ferments mannitol

    • blood agar : golden yellow

    beta haemolysi (complete)

    Tema principal

    le falta

    Virulence Factor & Pathogenesis

    exotoxins
    haemolysin
    protein A

  • combines with non-specifically with Fc-portion of IgG
  • inhibit opsonization

    • invasins

  • leucocidin-acts on PMN & macrocyte
  • staphylokinase & hyaluronidase-dessiminase

    • clumping factor

  • fibrogen-binding protein
  • important adhesin
  • leads to traumatized tissue and blood clot

    • staphylocoagulase

  • extracellular pt (fibronogen>fibrin)
  • fibrin-for protection from immunology

    • -localization of disease

    Marphology

    opaque,pigmented colonies
    catalase +ve
    arranged in cluster (grape-like)
    spherical cocci
    gram +ve

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