Eicosanoids

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Eicosanoids

Eicosa (Greek) - Twenty

TWO ENZYMES

Leukotrienes

Chemotaxis of leukocytes

PROSTANOIDS

Promotion sleep, fever heat Inducing Pain inhibiting pain swelling

Inflammation

Asprin/NSAIDS

Down regulation of eicosanoid synthesis

20 Carbon Essential Fatty Acids

Dihomo-gammi-linolenic Acid

3 Double Bonds

Omega 6

Proinflammatory

4 Double Bonds

Omega 3

5 Double Bonds

Signaling Molecules

Not Stored in Cells

Immunity

Leukocyte Chemotaxis

Stimulation of Platelet aggregation

Inhibition of platelet aggregation