Категории: Все - replication - genetics - meiosis - dna

по Nicholas Nguyen 6 лет назад

272

Genetic Variance

Genetic Variance

Genetic Variance in Humans

Examples

Meiosis
Eye color, Skin color, Hair color
DNA Replication Error
Sickle-Cell Anemia, Seasonal Flu Virus (new strains)
Cancer, Cystic Fibrosis, Crohn's Disease

Environmental Influence/Mutagens - outside agents that alters the genetic code.

Mutagens
Biological - altering DNA structure or replication via living organism, disrupting check and repair systems.
Virus
Bacteria
Chemical - chemicals that directly interact with DNA causing breakage or altering structure. Chemicals that can indirectly damage/alter DNA by enabling the creation of mutagenic compounds.
Metals
Deaminating Agent
Alkylating Agent
Intercalating Agent
Base Analog
Physical - radiation and particles damage or alter DNA structure or replication.
Heat
X-Ray
UV

DNA Replication Error - errors in replication can cause minor to significant changes in a genetic sequence.

Subtopic
Subsitution - replacing a codon or sequence with the same number of codons within a DNA strand.
Deletion - losing or "deleting" a codon or sequence from a DNA strand.
Insertion - adding or "inserting" a codon or sequence to a DNA strand.

Meiosis - the process to create gametes (egg and sperm cells) that have 1/2 the number of chromosomes as regular cells.

Crossing Over
Independent Assortment - alleles/genetic traits are inherited independently of each other (higher chance of variation).
Random Segregation - the random division of chromosomes into 4 separate gametes.
Crossing Over - the formation of recombinant chromosomes during prophase I, allowing exchange of genetic material between homologous chromosome pairs resulting in non-identical sister chromatids.