Rhabdomyolysis with Crush Injury
Renal ischemia
Free radical formation
Non-pharmacologic interventions
Pharmacologic interventions
Hyperphosphatemia
Hypocalcemia
Aggressively correct hypovolemia
metabolic acidosis
Mannitol
Myalgia and weakness
Buildup of lactic acid
Muscle Ischemia
Treat hypokalemia
Acute tubular necrosis
Strict I&Os
Monitor Labs
Fluid management
RAAS activation, SNS activation, ADH release
Renal constriction
Allopurinol
Hypovolemia
Half-isotonic saline with sodium bicarbonate
Low pH of urine
Decrease in GFR
Distal tubular obstruction
Filtered through kidneys
Causes myoglobinuria
Buildup causes cast formation
Release of intracellular contents into the bloodstream
Nucleotides
liver
increase of uric acid in kidneys
Cardiac Arrhythmias
Myoglobin
Hyperkalemia
Compression of muscle due to inelastic fascia
Crush injury
Muscle swelling due to trauma
Lysis of skeletal muscle cells
Compartment Syndrome
Nursing interventions
Increased uric acid concentration?
Rhabdomyolysis
