Thrombocytopenia

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Thrombocytopenia

Splenic sequestration

Liver dz w/ portal HTN

Peripheral destruction

Immune

ITP (Idiopathic)

a/w other auotimmune

a/w HIV

Nonimmune

TTP

DIC

Underproduction

Marrow toxins

EtOH

Infxn

Radiation

Drugs

Marrow infiltration

Granulomatous diseases

Fibrosis

Lymphomas

Leukemias

Tumors

Marrow failure

Vitamin deficiencies

Aplastic anemia

Myelodysplasia