ANEMIA of CHRONIC INFLAMMATION

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Aids

Scaleny Dakkにより

My Patient Rectal Sheath Hematoma, Anuric Acute Kidney Injury, Recent PE, Recent COVID Pneumonia

Kailey Taksにより

shp2

yu hoにより

CELIAC DISEASE

Jasdip Manak - Williams Parkway Sr PS (1424)により

Treatments

Erythropoisis stimulating agents

Treat inflammation

Treat underlying cause of inflammation

Blood transfusions

DIAGNOSTIC LABS

Increased Ferritin levels

Low serum iron

Decreased Transferrin saturation

CBC - low RBCs

Brenda Mitchell

Liver

Bone Marrow

Pluripoint stem cells

Proerythroblasts

Multiple divisions

accumulates Hemoglobin

Nucleus lost

Loses mitochondria and ribosomes

Reticulocytes released into circulatory system

Mature Red Blood Cells

Spleen

Iron stored as Ferritin

ANEMIA of CHRONIC INFLAMMATION

Systemic Inflammation

Auto Immune diseases, Infections, Malignancies, Burns, Trauma

Increased Cytokine production

Decrease Iron availability

Increased RBC Destrucion

Decrease RBC productio